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Manisha Gupte

Manisha Gupte

Associate Professor

Biology

  • Contact

  • guptem@apsu.edu
  • 931-221-6437
  • Sundquist Science Complex Room SSC C225

 

  • Ph. D. University of Kentucky (Division of Nutritional Sciences, College of Medicine; Focus: Obesity-Induced Hypertension), 2011

  • M.S. University of Kentucky (Division of Nutritional Sciences, College of Medicine; Focus: Clinical Nutrition), 2008

  • Human Anatomy and Physiology

  • Principles of Biology I

  • Cell and Molecular Biology

  • Obesity

  • Heart Failure

  • Type 2 Diabetes Mellitus

  • Lemon, J.J.; Ogbu, C.; Gupte, M. - Role and Regulation of Glycogen Synthase Kinase-3 in Obesity-Associated Metabolic Perturbations. Kinases Phosphatases 2024, 2, 279-293

  • Gupte M, Umbarkar P, Lemon J, Tousif S, Lal H. - Animal models of haploinsufficiency revealed the isoform-specific role of GSK-3 in HFD-induced obesity and glucose intolerance. Am J Physiol Cell Physiol. 2024

  • Gupte M, Tousif S, Lemon JJ, Toro Cora A, Umbarkar P, Lal H. - Isoform-Specific Role of GSK-3 in High Fat Diet Induced Obesity and Glucose Intolerance. Cells. 2022

  • Gupte M, Umbarkar P, Singh AP, Zhang Q, Tousif S, Lal H. - Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity. Cells. 2020

  • Gupte M, Tumuluru S, Sui JY, Singh AP, Umbarkar P, Parikh SS, Ahmad F, Zhang Q, Force T, Lal H. - Cardiomyocyte-specific deletion of GSK-3β leads to cardiac dysfunction in a diet induced obesity model. Int J Cardiol. 2018

  • Manisha Gupte, Hind Lal, Firdos Ahmad, Douglas B Sawyer, Michael F Hill. - Chronic Neuregulin-1β Treatment Mitigates the Progression of Post-Myocardial Infarction Heart Failure in the Setting of Type 1 Diabetes Mellitus by Suppressing Myocardial Apoptosis, Fibrosis and Key Oxidant-Producing Enzymes. J Card Fail. 2017

  • Manisha Gupte, Prachi Umbarkar, Hind Lal. - Mechanistic Insights of Empagliflozin-Mediated Cardiac Benefits: Nearing the Starting Line. Cardiovasc Drugs Ther. 2017

  • Jason M. Spaeth*, Manisha Gupte*, Holly Cyphert, Mark Christopher Wright, Mark Magnuson, Joseph Bass, Roland Stein. - Defining a novel role for the Pdx1 transcription factor in islet β cell maturation and proliferation during weaning. Diabetes 2017