EDUCATION:

Bachelor of Arts in Zoology, University of Tennessee, Knoxville, TN. Graduated with High Honors. 1981.

Ph.D., Graduate Program in Physiology and Pharmacology, School of Medicine, University of California, San Diego. 1991.

"Paracrine Regulation of Amnion Prostaglandin E₂ Biosynthesis" 

PROFESSIONAL EXPERIENCE:

Research Assistant, Department of Zoology, University of Tennessee, Knoxville, TN.
Electron and light microscopy including photomicrography and cell culture, radioimmunoassay, chromatography. 1981-1985.

Teaching Assistant, Department of Biology, University of California, San Diego, La Jolla, CA.
Conduct discussion sections for general biology. 1987.

Research Specialist, Department of Animal Sciences, University of Arkansas, Fayetteville, AR.
Conduct independent research as well as manage the laboratory activities of graduate and undergraduate students who are under the supervision of Dr. David L. Kreider. January 1992-July 1993.

Instructor, Baptist School of Nursing, Fayetteville, AR.
Teaching anatomy and physiology course for nursing students. 1992-1993.

Assistant Professor, Department of Biology, Austin Peay State University, Clarksville, TN.
Teaching responsibilities: human anatomy and physiology, general biology, cell and molecular biology, embryology. Research topics in mammalian reproductive physiology. August 1993-July 1997.

Associate Professor, Department of Biology, Austin Peay State University, Clarksville, TN.
Teaching responsibilities: cell and molecular biology, general biology, human anatomy and physiology, embryology, graduate level cell physiology. Research topics in mammalian reproductive physiology. August 1997-Present.

Faculty Internship, Office of Grants and Sponsored Programs, Austin Peay State University, Clarksville, TN. January 1999 - December 2000. Research Compliance.

ACADEMIC HONORS AND AWARDS:

1979-1980 Upperclassman Roddy Scholarship (University of TN)

1978-1979 Agricultural Scholarship (University of TN)

1981 Graduated with High Honors (University of TN)

1981 Phi Beta Kappa Honor Society

1998 Nominee: Alumni Distinguish Faculty Award (Austin Peay State University)

1999 Phi Kappa Phi Honor Society

GRANTS FUNDED

1992 Cooperative State Research Service Award - Research Grant from United States Department of Agriculture, Project Title: Uterine Oxytocin Receptors During Porcine Gestation (University of AR). Project #92-37208-8184. $43,750.00

1994 Austin Peay State University Tower Grant, Project Title: Porcine Endometrial Cell Primary Cultures: A Model for Examining Oxytocin Receptor Expression. (APSU) $820.00

1995 National Science Foundation Instrumentation and Laboratory Improvement Award, Project Title: Enhancing the Cell Biology Curriculum at Austin Peay State University. (APSU) Project #BWE-9550850. $39,830.00

1996 Austin Peay State University Tower Grant, Project Title: Characterization of Porcine Endometrial Cell Cultures and Their Use as a Tool for the Study of Oxytocin Receptor Expression. (APSU) $3,593.00

PUBLICATIONS IN REFEREED JOURNALS:

1. Duckett KE, Schiller SL, Girard PR, Kennedy JR. The effects of gossypol on the ultrastructure and function of tracheal ciliated cells. J Submicrosc Cytol 18(1):117-125, 1985.

2. Harris AN, Perlman M, Lundin-Schiller S, Romero R, Mitchell MD. Characterization of prostaglandin production in amnion-derived WISH cells. Am J Obstet Gynecol 159:1385-1389, 1989.

3. Lundin-Schiller S, Gibb W, Mitchell MD. Amnion cell prostaglandin E₂ stimulatory activity in chorion laeve conditioned medium. Biochim Biophys Acta 1053:151-155, 1990.

4. Mitchell MD, Dudley DJ, Edwin SS, Lundin-Schiller S. Interleukin-6 stimulates prostaglandin production by human amnion and decidual cells. Eur J Pharmacol 192:189-191, 1991.

5. Lundin-Schiller S, Mitchell MD. Renin increases human amnion cell prostaglandin E₂ biosynthesis. J Clin Endocrinol Metab 73:436-440,1991.

6. Mitchell MD, Lundin-Schiller S, Edwin SS. Endothelin production by amnion and its regulation by cytokines. Am J Obstet Gynecol 165:120-124,1991.

7. Lundin-Schiller S, Mitchell MD. Prostaglandin production by human chorion laeve cells in response to inflammatory mediators. Placenta 12:353-363,1991.

8. Mitchell MD, Edwin SS, Lepera R, Lundin-Schiller S. Epidermal growth factor and the regulation of amnion prostaglandin biosynthesis. Prostaglandins Leukotrienes EFA 44:57-59,1991.

9. Dowling DD, Romero RJ, Mitchell MD, Lundin-Schiller S. Isolation of multiple substances in amniotic fluid that regulate amnion prostaglandin E₂ production: the effects of gestational age and labor. Prostaglandins Leukotrienes EFA 44:253-255,1991.

10. Lundin-Schiller S, Mitchell MD. Regulation of chorion laeve prostaglandin E₂ production by epidermal growth factor, protein kinase C and calcium. Placenta 12:597-603,1991.

11. Dudley DJ, Trautman MS, Edwin SS, Lundin-Schiller S, Mitchell MD. Biosynthesis of interleukin-6 by human chorion laeve cells: regulation by cytokines. J Clin Endocrinol Metab 75(4): 1081-1086, 1992.

12. Mitchell MD, Edwin SS, Lundin-Schiller S, Silver R, Smotkin D, Trautman MS. Mechanism of interleukin-1_B stimulation of human amnion prostaglandin biosynthesis: mediation via a novel inducible cyclooxygenase. Placenta 14:615-625, 1993.

13. Lundin-Schiller S, Kreider DL, Rorie RW, Hardesty D, Mitchell MD, Koike TI. Characterization of porcine endometrial, myometrial and mammary oxytocin binding sites during gestation and labor. Biol Reprod 55:575-581, 1996.

NON-REFEREED AND REVIEW ARTICLES:

1. Mitchell MD, Romero R, Gibb W, Harris AN, Dowling DD, Lundin-Schiller S. The regulation of prostaglandin biosynthesis during human labor. Prostaglandins and Labor, Vol.5, Belfort P, Pinotti JA, and Eskes TKAB (Eds.), Parthenon Publishing, Carforth, pp. 11-18, 1989.

2. Lundin-Schiller S, Mitchell MD. The role of prostaglandins in human parturition. Prostaglandins Leukotrienes EFA 30:1-10,1990.

3. Mitchell MD, Lundin-Schiller S. The regulation of arachidonic acid metabolism in pregnancy. Uterine Contractility: Mechanisms of Control. Serono Symposia, USA. (Garfield E, ed) Plenum Publishing, Boston, MA, 1990, pp. 205-219.

4. Mitchell MD, Branch DW, Lundin-Schiller S, Romero RJ, Daynes RA, Dudley DJ. Immunologic aspects of preterm labor. In: Seminars in Perinatology, (Scott J, ed.) W.B. Saunders Co., Philadelphia PA, 1991, pp. 210-224.

5. Mitchell MD, Adamson S, Coulam C, Romero RJ, Lundin-Schiller S, Trautman MS. The roles and regulation of prostaglandins within the uterus. In: Control of Uterine Contractility, (Garfield RE and Tabb TN, eds.) CRC Press, Boca Raton, FL. 1994, pp. 255-283.

ABSTRACTS (Presenting author in bold):

1. Durrant BS, Ratanaswamy MJ, Schiller SL. Survival and penetration of cryopreserved hamster ova. American Society of Andrology, Houston, TX, 1988.

2. Harris AN, Perlman M, Lundin-Schiller S, Romero R, Mitchell MD. Characterization of prostaglandin production in amnion-derived WISH cells. Proceedings of the Annual Meeting of the Society for Gynecologic Investigation, Baltimore, MD, 1988, p.244 Abstract #370. (Poster)

3. Lundin-Schiller S, Gibb W, Mitchell MD. Stimulation of amnion eicosanoid biosynthesis by a substance(s) from chorion laeve. Proceedings of the Annual Meeting of the Society for Gynecologic Investigation, Baltimore, MD, 1988, p.244 Abstract 371. (Poster)

4. Mitchell MD, Stavros FD, Romero R, Varticovski L, Gibb W, Lundin-Schiller S. The regulation of arachidonic acid metabolism and human parturition. Proceedings of the Centennial Symposium on Fetal and Neonatal Development, London, Ontario, 1988, Abstract #4. (Oral)

5. Lundin-Schiller S, Gibb W, Mitchell MD. Characterization of a substance(s) secreted by chorion laeve that stimulates amnion cell prostaglandin E₂ production. Proceedings of the 70th Annual Meeting of the Endocrine Society, New Orleans, LA, 1988, p. 166, Abstract #581. (Poster)

6. Mitchell MD, Stavros FD, Romero R, Varticovski L, Gibb W, Lundin-Schiller S. The control of prostaglandin biosynthesis in human amnion cells. Proceedings of the First European Congress on Prostaglandins in Reproduction, Vienna, Austria, 1988, p. 18, Abstract #87. (Oral)

7. Mitchell MD, Lundin-Schiller S, Harris AN. The regulation of eicosanoid biosynthesis in amnion cells and amnion derived WISH cells: a comparison. Proceedings of the Liggins Symposium: Fetal Physiology and Medicine, Rotorua, New Zealand, 1988, Abstract #P63. (Oral)

8. Dowling DD, Mitchell MD, Lundin-Schiller S. Isolation of multiple substances from amniotic fluid that regulate amnion prostaglandin E₂ production: the effects of gestational age and labor. Proceedings of the Annual Meeting of the Society for Gynecologic Investigation, San Diego, CA, 1989, p. 288, Abstract #414. (Oral)

9. Lundin-Schiller S, Mitchell MD. Induction of fatty acid cyclooxygenase protein biosynthesis in human amnion as a mechanism for interleukin-1ß stimulated biosynthesis and labor. Proceedings of the 71st Annual Meeting of The Endocrine Society, Seattle, WA, 1989, p.388, Abstract #1264. (Oral)

10. Mitchell MD, Edwin SS, Lundin-Schiller S. Endothelin production by cells derived from gestational tissues. Proceedings of the Annual Meeting of the Society for Gynecologic Investigation, St. Louis, MO, 1990, p.171, Abstract #149 (Poster)

11. Lundin-Schiller S, Mitchell MD. Does chorionic renin regulate amnion cell prostaglandin E₂ biosynthesis? Proceedings of the Annual Meeting of the Society for Gynecologic Investigation, St. Louis, MO, 1990, p. 194, Abstract #195. (Oral)

12. Mitchell MD, Lundin-Schiller S. The regulation of arachidonic acid metabolism in women. Proceedings of the Serono Symposia on Uterine Contractility: Mechanisms of Control, St. Louis, MO, 1990, p.18. (Oral)

13. Dudley DJ, Mitchell MD, Lundin-Schiller S. Human chorion laeve cells produce copious amounts of interleukin-6 (IL-6) after stimulation with other inflammatory cytokines and endotoxin. Proceedings of the Annual Meeting of the Society for Gynecologic Investigation, San Antonio, TX, 1991, p.148, Abstract #99. (Poster)

14. Lundin-Schiller S, Mitchell MD. Regulation of prostaglandin (PG) production in human chorion laeve cells: effect of time in culture. Proceedings of the Annual Meeting of the Society for Gynecologic Investigation, San Antonio, TX, 1991, p.236, Abstract #275. (Poster)

15. Lundin-Schiller S, Edwin SS, Mitchell MD. The regulation of arachidonate lipoxygenase metabolite production in gestational tissues. Presented at the Second European Congress on Prostaglandins in Reproduction, The Hague, the Netherlands, 1991. (Poster)

16. Mitchell MD, Edwin SS, Lepera R, Lundin-Schiller S. Epidermal growth factor and the regulation of human amnion prostaglandin biosynthesis. Accepted for presentation at the Summer Meeting of the Society for the Study of Fertility, Oxford, England, 1991, Abstract #78. (Poster)

17. Lundin-Schiller S, Mitchell MD. Mechanism(s) of interleukin-1ß stimulation of human amnion cell prostaglandin E₂ biosynthesis. Accepted for presentation at the Summer Meeting of the Society for the Study of Fertility, Oxford, England, 1991, Abstract #135. (Poster)

18. Dicker A, Kreider D, Lundin-Schiller S. Effects of oxytocin and GnRH on the release of LH from bovine anterior pituitary cell cultures with and without phenol red. Journal of Animal Sciences Vol 71, Suppl 1, 1993, Abstract #490. (Oral)

19. Kreider D, Cole D, Rorie RW, Dicker A, Schiller S, Miller F, and Gleidt D. Effects of active immunization against androgenic steroid precursors on ovulation rate and litter size in gilts. Journal of Animal Sciences Vol 71, Suppl 1, 1993, Abstract #498. (Oral)

20. Lundin-Schiller S, Kreider DK, Rorie RW, Hardesty D, Mitchell MD, Koike TI. Characterization of oxytocin binding sites in porcine endometrium, myometrium and mammary tissues during gestation and labor. Society for the Study of Reproduction, 28th Annual Meeting, Davis, CA, 1995, Abstract #507. (Poster)

21. Hahn AM, Lundin-Schiller S. Morphological and Histochemical Characterization of Porcine Endometrial Cells In Vitro. Tennessee Academy of Science, 107^th Annual Meeting, Tullahoma, TN, 1997. (Poster)

22. Haldeman K, Lundin-Schiller S. Regulation of ³H-Oxytocin Binding Sites in Porcine Myometrial Cell Monolayer Cultures. Tennessee Academy of Science, 107^th Annual Meeting, Tullahoma, TN, 1997. (Oral)

23. Mells J, Lundin-Schiller S. Expression of ³H-Oxytocin Binding Sites in Porcine Luminal Endometrial Cells In Vitro: Regulation by Steroid Hormones. Tennessee Academy of Science, 107^th Annual Meeting, Tullahoma, TN, 1997. (Oral)

24. Haldeman K, Lundin-Schiller S. Does Retinoic Acid Alter the Effects of Estrogen Treatment on Endometrial and Myometrial Oxytocin Receptor Expression In Vitro? Tennessee Academy of Science, 108^th Annual Meeting, Cookeville, TN. 1998 (Poster)

WORKSHOPS/SYMPOSIA ATTENDED:

Techniques in Reproductive Biology Workshop: Confocal Microscopy. Hosted by Society for the Study of Reproduction held at University of California, Davis, July 9, 1995.

Southern Regional Grants Workshop presented by USDA National Research Initiative Competitive Grants Program, hosted by Alabama Agricultural Experiment Station and held at Atlanta Marriot, Atlanta, GA, November 27, 1995.

Techniques in Reproductive Biology Workshop: Novel Approaches for the Detection and Analysis of Functional Protein-Protein and Protein-DNA Interactions. Hosted by Society for the Study of Reproduction held at Jantzen Beach Hotel, Portland, OR, August 2, 1997.

Seventh Annual University of Kentucky Symposium in Reproductive Sciences, Lexington, KY, May 15 & 16, 1998.

1st International Symposium on Assisted Reproductive Technology for the Conservation & Genetic Management of Wildlife, Henry Doorly Zoo, Omaha, NB, January 17-18, 2001.

Contessa Morgan, Summer 1995

Kurt Haldeman, 1997 - 1999

Jamie Mells, 1996 - Present

Lorenzo E. Altamon, 1999-Present

Angela Hahn, Project Title: Morphological and Histochemical Characterization of Porcine Endometrial Cells In Vitro. Summer 1997

Judy McElhiney, Project Title: Characterization of a PGF2alpha Radioimmunoassay. Fall 2002

Katrine Jensen, Project Title: Stimulation of Porcine Endometrial Cell Growth by Estradiol In Vitro. Spring 2003.

COURSES TAUGHT [Course Descriptions]

General Biology (Biology 1010, 1020, 1110)

Human Anatomy and Physiology (Biology 2010, 2020)

General Embryology (Biology 4200)

Cell and Molecular Biology (Biology 4440)

Cell and Molecular Biology (Biology 5440)

PROFESSIONAL MEMBERSHIPS:

The Endocrine Society

Society for the Study of Reproduction (SSR)

Member of Education Committee for SSR 1996-1998

Tennessee Academy of Science

UNIVERSITY SERVICE:

Library Committee, 1994-1995

Human Research Review Committee, 1996-2001

Search Committee: Medical Technology Program Director, Spring 1998

Faculty Advisor for Tri-Beta Biological Honor Society, 1998-2001

Departmental Radiation Safety Officer, Fall 1998-Present

Animal Use and Care Committee, Fall 2000-present

Chair Search Committee: Director of Grants & Sponsored Programs, Summer/Fall 2001

Presidential Research Scholarship Proposal Reviewer, Spring 2001-Spring 2002

Presidential Research Scholarship Steering Committee, Fall 2002-Present

Chair of Scientific Review Committee for Middle TN Science & Engineering Fair, Fall 2003-Spring 2004

Departmental Curriculum Committee, Spring 2003 – Present

Departmental Secretary Search Committee, Fall 2003

Departmental Laboratory Manager Search Committee, Spring 2004

OTHER PROFESSIONAL & COMMUNITY SERVICE:

Ad Hoc Grant Reviewer for USDA-CSREES, 1996-Present

Abstract Reviewer for 1998 Annual Meeting of the Society for the Study of Reproduction

Moderator for Collegiate Division of TN Academy of Science, APSU, April 1998

Board Member, Warioto Chapter of the National Audubon Society, Fall 1998-Present