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Dr. Brian Hock

 

Assistant Professor
Department of Psychology
Austin Peay State University
Clarksville, TN 37044

Office: Clement 223E
Phone: (931)221-1045
Fax: (931)221-6267
Email: hockb@apsu.edu
 

I joined the faculty at APSU in 2005 following a one-year visiting position at Denison University.  I also completed a postdoctoral fellowship at Case Western Reserve University in the Department of Genetics.  I will be teaching Statistics, Introductory Psychology, Physiological Psychology and Learning and Motivation.

 Research Interests

 My research interests are to identify the role of the dorsal     and ventral poles of the hippocampus in learning and memory.  This interest began after the important case studies of H.M. by Drs. Scoville and Brenda Milner.  Briefly, Dr. Scoville removed the hippocampus from H.M. to reduce epileptic seizures.  The consequences of that surgery reduced the severity and number of seizures, however, H.M. could no longer retain certain types of memory (anterograde amnesia), and had amnesia for recent past events (retrograde amnesia).  My interests since that time have been to identify what types of memory subserve the different anatomical regions of the hippocampus, more specifically, the ventral hippocampus.  

My second interest the biological and environmental factors that affect learning and memory across species.  I have studied the pathological consequences on learning and memory in different transgenic mouse models of Alzheimer's disease (AD).  This research has suggested that different pathological events of AD produce dependent and independent memory deficits.  This research has serious implications for drugs that focus treatment on one pathological event, such as extracellular plaques, but may not alleviate the symptoms resulting from neurofibrillary tangles.  Another interest is how do such events, such as life-long learning or environmental enrichment, affect the production of pathology and dementia in Alzheimer's disease.  This interest is the result of the Nun Study at the University of Kentucky. 

Publications and Presentations

 Co-authored Works with Students

 Petriello, M.C., Hock, B.J. and Lamb, B.T. (2003).     Learning and memory impairments between different mouse     models of Alzheimer's disease. The Second Annual Senior     Capstone Fair, Case Western Reserve University

 Hock, B.J., Price, B., & Bunsey, M.D. (1999). The role of the ventral hippocampus in learning and memory. Society for Neuroscience Abstracts, Vol. 29.

 Selected Publications

 Hock, B.J., Lattal, K.M., Shapiro Kulnane, L., Abel, T.  & Lamb, B.T. (In Prep). Pathology dependent and     independent memory deficits in yeast artificial chromosome     amyloid precursor protein transgenic mice.

Hock, Shapiro Kulnane, L., Lehman, E.J.H., Hock, B.J.,     Tsuchiya, K.D. & Lamb, B.T. (2002). Rapid and Efficient     Detection of Transgene Homozygosity by FISH of Mouse     Fibroblasts. Mammalian Genetics, 13(4), 223-226.

Hock, B.J. & Lamb, B.T. (2001). Transgenic mouse models of Alzheimer's Disease. Trends in Genetics, 17(10): S7-S12.

Hock, B.J. & Bunsey, M.D. (1998). Differential effects of dorsal and ventral hippocampal lesions. Journal of     Neuroscience, 18(17): 7027-7032.

   

Department of Psychology
Austin Peay State University
P.O. Box 4537
Clarksville, TN 37044
(931)221 - 7233
deshont@apsu.edu